Olympiacos also defeated Monaco in the second match in Piraeus 94:64.
Giorgos Barcokas' team was up 21 points (91:70) two days ago.
The triumph of the "red and whites" was never in question, and when the guests were left without the suspended James in the second quarter, everything was clear.
Monaco then lost their best player, Mike James, who was sent off for protesting to the referees. To make matters worse, the visitors only scored eight points in that quarter.
There was almost a 30-point difference at halftime...
Vezenkov led Olympiacos with 21 points and seven rebounds. Fournier added 13, along with seven assists and four rebounds, while Vocap also scored in double figures with 10 points.
The best players for Monaco were Hayes with 11 and Diallo with 10 points.
The third match will be played on May 5th in Monte Carlo.
Fenerbahçe defeated Zalgiris in Istanbul 86:74.
On the wings, Nikola Melija shot 6-6 from the field, and Fenerbahce had a huge 51:33 lead at halftime.
There was no more return for Žalgiris.
The most efficient player of the game was Meli with 17 points, Nando de Colo had 16, Tarik Biberović 15,.
On the other side, the duo of Tubelis and Wright scored 16 points each.
